Polio virus, sign symptom and diagnosis


Poliomyelitis

Causative agent →poliovirus (serotype 1,2&3)
P1→ Mcc of epidemics
P2 → most antigenic and most easily eradicable
P 3 → MCC of VAPP (vaccine associated paralytic poliomyelitis)

Reservoir: Man (No chronic carrier )
Mc clinical occurrence : sub clinical case
Infectious material : feaces & oro-pharyngeal Secretions
Period of communicability: 7-10 days before and after onset of symptom
Incubation period : 3 to 35 days
Clinical Presentation 
⇒ HISTORY OF FEVER AT ONSET OF PARALYSIS is suggestive of polio
⇒ There is NO SENSORY LOSS in polio.

Diagnosis

1. Stool examination - Reverse cold chain in red box.
virus can be found in feces from Onset to upto 8 weeks after paralysis with max. probability in first 2 weeks.
2. CSF examinations
3. Throat examination
4. Blood examination














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